肺癌靶向治疗致自身免疫性疾病相关间质性肺疾病进展两例并文献复习

<正>在晚期非小细胞肺癌的治疗中,靶向治疗是有特定驱动基因突变患者的一线方案,但靶向治疗存在诱发间质性肺疾病(Interstitial lung disease,ILD)风险,约为0.4%~6.0%。本文报道了我科收治的两例自身免疫性疾病相关间质性肺疾病(autoihttp://www.selleckchem.commmune diseases-related interstitial lung disease,AIDILD)合并肺癌患者。一例为显微镜下多血管炎相关间质性肺疾病(Microscopic pohttp://www.selleckchem.comlyangiitis withinterstitial lung disease,MPA-ILD),一例为自身免疫特征的间质性肺炎(Interstitial pneumonia withttp://www.selleckchem.comh autoimmune features,IPAF),

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